中药制何首乌的研究进展摘要：中药何首乌别名首乌、赤首乌，为蓼科蓼属植物何首乌Polygonum multiflorum Thunb. 的干燥块根，主产于我国四川、湖南、贵州、河南等省区，生于灌木丛中、山脚阴处或石隙中。
何首乌是一味较常用的滋补肝肾的中药，记载初见于宋初《开宝本草》，味苦、甘、涩而性温，主入肝、肾、心经，具有补益精血、解毒、润肠通便、补肾等作用。
制何首乌为何首乌的炮制加工品，味苦、甘、涩，性温，归肝、心、肾经，能补肝肾，益精血，乌须发，强筋骨。
本文拟对何首乌的基原，化学成分，炮制工艺，药理作用等方面的研究进展做一综述，供相关研究参考。
关键词：制何首乌；基原；炮制；药理作用；Abstract: The traditional Chinese medicine Polygonum multiflorum thunb. is also known as Shouwu and Red Shouwu. It is the dry root of Polygonaceae P. muultiflorum. It is mainly produced in Sichuan, Hunan, Guizhou, Henan and other provinces in my country. It is born in bushes, shady places or rocks In the gap. Polygonum multiflorum thunb. is a more commonly used traditional Chinese medicine for nourishing the liver and kidney. It was first recorded in 'Kaibao Materia Medica' in the early Song Dynasty. It tastes bitter, sweet, astringent and has a warm nature. It mainly enters the liver, kidney and heart meridian. It has the function of nourishing essence and blood, detoxifying and moisturizing. Intestinal laxative, tonifying kidney and other effects. The processed products of Polygonum multiflorum are bitter, sweet, astringent, warm in nature, and return to the liver, heart, and kidney meridian. It can nourish the liver and kidney, nourish essence and blood, black hair, and strengthen bones and muscles. The four aspects of Polygonum multiflorums origin, chemical composition, processing technology, and pharmacological effects are reviewed for reference in related research.Key words: Polygonum multiflorum thunb. ; Foundation; refine; Pharmacological effect1. 基原1.1本草考证《本草纲目》记载：该药气温，味苦涩。
苦补肾，温补肝，涩能收敛精气，所以能养血补肝，固精益肾，健筋骨，乌须发，为滋补良药[1]。
何首乌有赤白两种，目前通用的主要是赤首乌，而白首乌的植物形态，药材性状，功效以及临床应用的特点均与蓼科何首乌相差甚远，应予以区别[2]。
1.2不同地区首乌的品质差异何首乌生长于海拔200-800米的丘陵，草坡和灌丛。
野生品分布于西南，中南，华东地区及陕西，甘肃等省。
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