摘 要：青娥丸首载于宋代，其应用历史悠久，对腰酸无力，不能久立远行、腰痛、脚气、头痛、慢性腰肌劳损及腰椎退行性病变、骨质增生等症有确切疗效。
现代研究发现青娥丸中的杜仲有降血压作用，还能减少机体对胆固醇的吸收，并具有消炎、利尿、抑菌及增加机体免疫力的功能；补骨脂能明显扩张冠状动脉，增加冠脉血流量，增强心肌收缩力，促进粒细胞生长；核桃仁补肾固精，主要成分为亚油酸，对防治动脉粥样硬化有独特功效；大蒜可提高机体免疫力，并可增强机体抗氧化、抗衰老的能力。
关键词：青娥丸；药代动力学；炮制技术Study on Pharmacokinetics of Qinge Wan in Rats before and after processingAbstract: Qinge Wan was firstly recorded in the Song dynasty,and its application has a long history.It has good effect on backache, weakness, can not long stand travel, back pain, athletes foot, headaches, chronic muscle strain and lumbar degenerative disease, osteoarthritis and some other diseases. Modern research has found that the Eucommia in Qinge Wan can make blood pressure lower, and it also can reduce the bodys absorption of cholesterol, and has function of anti-inflammatory, diuretic, antibacterial and increase the bodys immune; Psoralen can significantly expand coronary artery, increase coronary blood flow, enhanced myocardial contractility, and promote the growth of granulocytes; Walnut is good to kidney , it mainly composed of linoleic acid which has a unique effect in the prevention of atherosclerosis; Garlic can improve immunity, and may enhance the bodys ability of anti-oxidant, anti-aging.Key Words: Qinge Wan; pharmacokinetics;processing传统中药炮制理论认为盐制入肾，盐炙后主入肾经，增强中药温肾壮阳，固精缩尿的功效。
肾为先天之本，肾主骨，生髓，髓藏于骨腔内滋养骨骼，骨骼的生长发育依赖肾中精气的滋养。
若肾精不足，骨髓的生长之源不足，不能濡养骨骼，会引发骨质疏松症，出现腰背酸痛、胫膝酸软等症状。
骨质疏松症是以骨量减少、骨组织显 微结构退化（松质骨骨小梁变细、断裂、数量减少，皮质骨多孔、变薄）为特征，以致骨的脆性增高及骨折危险性增加的一种全身性、代谢青娥丸首载于宋代，是以温肾助阳为基本功能的延年益寿药。
青娥丸方名来自于一首古诗。
其诗曰：三年时节向边隅，人见方知药力殊，夺得春光来在手，青娥休笑白髭须。
青娥乃年轻女子之别称。
该诗大意是说，服此药后能使人恢复青春，另性机能强健。
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